Table of Contents
- Neuroscience, hearing and revalidation
- Positions & experience
- Showcase projects
- Online stuff
Neuroscience, hearing and revalidation
My work in the field of auditory neuroscience and audiology focusses on the question how basic features of sound, such as frequency, are mapped in the human auditory cortex. In addition, I’m interested in changes in these maps following e.g., hearing loss and tinnitus and whether hearing aids have an impact on these maps.
For this I use state-of-the-art imaging technology (high-resolution fMRI at high and ultra-high fields and high-density EEG) and analyses methods (surface-based processing and pattern classification analysis of fMRI data, and independent component analysis of EEG data).
In addition to basic neuroscience, I’ve started working as an audiologist-in-training (in Dutch: klinisch fysicus-audioloog in opleiding; see the NVKF-link for more information). This training position is geared towards assessment and rehabilitation of hearing in hearing-impaired subjects. This work is closely linked to, and guided by, basic neuroscience of hearing. This combination of both worlds is hopefully beneficial to the hearing-impaired population.
Positions & experience
2015 – now — Board member of KLIFOP. As a board member I represent the Klinisch Fysici in Opleiding (Klifio’s) and take part in the committee Education and Research (O&O) of the Nederlandse Vereniging Klinische Fysica (NVKF).
2009 – 2013 — Career Development Fellow, MRC Institute of Hearing Research , Nottingham, United Kingdom.
2005 – 2009 — PhD “Functional Magnetic Resonance Imaging of Tinnitus” Faculty of Medical Sciences, University Medical Center Groningen. Promotor(s): prof.dr. P. van Dijk and dr. ir. E. de Kleine. Date : 31 March 2010, 16.15h. pdf file (8Mb!)
1999 – 2005 — Applied Physics (University of Groningen), Master Biomedical Engineering — Medical Imaging and Instrumentation. Masters thesis: Perfusion Imaging using Arterial Spin Labeling. Graduation: May 2005
Here are some project that are worth mentioning. Well, at least from my perspective…
Recently we published the proceedings of the 17th International Symposium on Hearing (ISH), 2015. It is available for download here (19 Mb!) or at the website of Springer. Thanks to all the contributions, we were able to compile this impressive book; open source = happy reading.
Stimulus choice for ABR threshold measurements
A student in biomedical engineering at the RUG has been working on a project at PENTO testing two types of stimuli for Auditory Brainstem Response (ABR) threshold measurements; the main question was whether one or the other was more suitable for measurements in neonates (those who get referred to us for failing an automated screening measures in the first week after birth). The main conclusion is that the ABR signal of peak V is significantly larger in Chirp-evoked ABR-responses than in conventional click-evoked ABR-responses. The figure shows the amplitude for many different levels for the two stimuli.
See the corresponding Jupyter Notebook on github for more details
Real ear measurements in infants
Verification of the amplification in hearing aids in infants is essential; not only do you want to reduce the risk of further hearing impairment due to wrongly fitted hearing aids, you certainly want to make sure the infant is stimulated to such a degree that the development of speech and language is actually possible.
In one of the latest projects, I’ve been implementing the real-ear measurements in infants with hearing loss. Especially by using the real-ear aided response (REAR) measurements, either in-situ in adults/adolescents (REAR/REIG) or the real-ear to coupler difference (RECD) in infants. Hearing aid verification using aided-responses allows us to visualize the amount of amplification needed and is now used as a counselling tool. In combination with the right test stimulus it also allows us to assess advanced signal processing applied in hearing aids, such as noise reduction or wide-band dynamic compression.
A list of publications: scientific papers, presentations and posters, books and book chapters, teaching and online material, interviews and other output.
See also: http://www.rug.nl/staff/c.p.lanting/research for the most recent (automated lists of) publications.
Lanting, C., Woźniak, A., van Dijk, P., & Langers, D. R. M. (2016). Tinnitus- and Task-Related Differences in Resting-State Networks. Advances in experimental medicine and biology, 894, 175-87. 10.1007/978-3-319-25474-6_19
Lanting, C. P., de Kleine, E., Langers, D. R. M., & van Dijk, P. (2014). Unilateral Tinnitus: Changes in Connectivity and Response Lateralization Measured with fMRI. PLoS ONE, 9(10), . 10.1371/journal.pone.0110704
Lanting, C. P., Briley, P. M., Sumner, C. J., & Krumbholz, K. (2013). Mechanisms of adaptation in human auditory cortex. Journal of Neurophysiology, 110(4), 973-983. 10.1152/jn.00547.2012
Lanting, C. P., de Kleine, E., Eppinga, R. N., & van Dijk, P. (2010). Neural correlates of human somatosensory integration in tinnitus. Hearing Research, 267(1-2), 78-88. 10.1016/j.heares.2010.04.006
Crippa, A., Lanting, C., Dijk, P. V., & Roerdink, J. B. T. M. (2010). A Diffusion Tensor Imaging Study on the Auditory System and Tinnitus. The Open Neuroimaging Journal, 4, 16-25. 10.2174/2F1874440001004010016.
Lanting, C. P., de Kleine, E., & van Dijk, P. (2009). Neural activity underlying tinnitus generation: Results from PET and fMRI. Hearing Research, 255(1-2), 1-13. 10.1016/j.heares.2009.06.009
Lanting, C. P., De Kleine, E., Van Dijk, P., & Bartels, H. (2008). Functional imaging of unilateral tinnitus using fMRI. Acta oto-Laryngologica, 128(4), 415-421. 10.1080/00016480701793743
Books, book chapters and reports
van Dijk, P., Başkent, D., Gaudrain, E., de Kleine, E., Wagner, A., & Lanting, C. (Eds.) (2016). “Physiology, Psychoacoustics and Cognition in Normal and Impaired Hearing.” Springer.
Hall, D. A., Lanting, C. P., & Hartley D. E. H. (2014) “Using fMRI to examine central auditory plasticity”; in “Advanced Brain Neuroimaging Topics in Health and Disease - Methods and Applications”; Edited by T. Dorina Papageorgiou, George I. Christopoulos and Stelios M. Smirnakis, ISBN 978-953-51-1203-7, 678 pages, Publisher: InTech. 10.5772/58262
Lanting, C.P. (2013). “Ik hoor, ik hoor wat jij niet hoort”. NVBRM 63(2) 2013.
Lanting, C. P., & van den Berg, G. P. (2003). Op zoek naar stilte: indicatoren van stilte in De Wieden/Weerribben, NP Utrechtse Heuvelrug en de Zak van Zuid-Beveland.
Presentations and posters
A list of (invited) talks and poster presentations
C.P. Lanting, A. Wozniak, P. van Dijk, D.R.M. Langers; `Tinnitus- and Task-Related Differences in Resting-State Networks’. 10th TRI Conference and 1st TINNET Conference in Nottingham, UK, March 16-18, 2016
C.P. Lanting, A. Wozniak, P. van Dijk, D.R.M. Langers; `Tinnitus- and Task-Related Differences in Resting-State Networks’. 17th International Symposium on Hearing (ISH), June 15-19 2015, Groningen, The Netherlands.
C.P. Lanting, A. Wozniak, P. van Dijk and D.R.M. Langers; ‘Tinnitus-related abnormalities in brain networks during stimulated and resting states’. 18th meeting of the Deutsche Gesellschaft fur Audiologie (DGA), March 5-7 2015, Bochum, Germany.
C.P. Lanting, E. de Kleine, D.R.M. Langers and P. van Dijk; ‘Unilateral tinnitus: changes in connectivity measured with fMRI’. 5th International Conference on Auditory Cortex, September 13-17 2014, Magdeburg, Germany.
C.P. Lanting; ‘Functional magnetic resonance imaging and tinnitus: from measuring sound-evoked responses to connectivity’. Seminar series, University of Oldenburg, Germany, July 10, 2014. (Invited lecture).
C.P. Lanting, K. Boyen, E. de Kleine, D. Langers, and P. van Dijk; ‘Reduced connectivity between brainstem and cortex in patients with tinnitus’. Wetenschappelijke bijeenkomst werkgemeenschap Auditief Systeem (WAS-dag), Leuven, Belgium, May 14, 2014.
C.P. Lanting and K. Krumbholz; ‘Non-invasive EEG and fMRI measures of frequency selectivity in human auditory cortex’. 4th International Conference on Auditory Cortex, August 31st - September 3rd 2012, Lausanne, Switzerland.
C.P. Lanting; ‘Measures of frequency selectivity in human auditory cortex - a multi-modal approach’. Symposium “Auditory Neuroimaging”, Delmenhorst, Germany, September 23, 2011 (Invited lecture).
C.P. Lanting,S. Francis, R. Bowtell and K. Krumbholz; ‘Frequency selectivity and local map structure in human auditory cortex measured with 7 Tesla fMRI’. BSA annual conference, Nottingham, United Kingdom, September 7–9, 2011.
C.P. Lanting, S. Francis, R. Bowtell and K. Krumbholz; ‘Frequency selectivity and local map structure in human auditory cortex measured with 7 Tesla fMRI’. OHBM 17th annual meeting, Quebec City, Canada; June 26–30, 2011.
C.P. Lanting, K. Krumbholz; ‘Using an adaptation paradigm to measure the resolution of frequency tuning in human auditory cortex’. BSA annual conference, Manchester, United Kingdom, September 9–10 2010.
C.P. Lanting, P. Briley, K. Krumbholz; ‘Stimulus specificity of adaptation in human auditory cortex’. OHBM 16th annual meeting, Barcelona, Spain, June 6–10 2010.
C.P. Lanting, R. Eppinga, E. de Kleine, P. van Dijk; ‘Somatosensory input to the auditory pathway in humans, an fMRI study’. 3rd Tinnitus Research Initiative Meeting, Stresa, Italy, June 24–26, 2009.
C.P. Lanting, E. de Kleine, P. van Dijk; ‘The response to sound of auditory brain areas in tinnitus patients’. ARCHES meeting, Haarlem, The Netherlands, November 24–25, 2008.
C.P. Lanting, E. de Kleine, P. van Dijk; ‘Somatosensory interaction in the auditory pathway in humans, an fMRI study.’ IXth International Tinnitus Seminars, Göteborg, Sweden, June 15–18, 2008.
E. de Kleine, C.P. Lanting, P. van Dijk; ‘Enhanced fMRI responses to sound in patients with unilateral tinnitus.’ IXth International Tinnitus Seminars, Göteborg , Sweden, June 15–18, 2008.
C.P. Lanting, E. de Kleine, P. van Dijk; ‘Increased fMRI responses to sound in the inferior colliculus and medial geniculate body in patients with unilateral tinnitus.’ 31st ARO midwinter meeting 2008, Phoenix, Arizona, USA.
C.P. Lanting, E. de Kleine, H.Bartels, P. van Dijk; ‘Responsies van het centrale auditieve systeem in tinnituspatiënten: een fMRI studie’. KNO vergadering, Nieuwegein, November 9, 2007.
C.P. Lanting, E. de Kleine, H.Bartels, P. van Dijk; ‘Functionele MRI in tinnituspatiënten’. Najaarsvergadering van de Nederlandse Vereniging voor Audiologie, Utrecht, September 28, 2007.
C.P. Lanting, E. de Kleine, P. van Dijk; ‘Functional Imaging of tinnitus, A study of tinnitus with unilateral tinnitus patients and normal hearing subjects’. Wetenschappelijke bijeenkomst werkgemeenschap Auditief Systeem (WAS-dag), Groningen, May 16, 2007.
C.P. Lanting; ‘Functional Imaging of tinnitus, A study of tinnitus with unilateral tinnitus patients and normal hearing subjects.’ Eaton Peabody Laboratory of auditory physiology, Boston, Massachusetts, USA, February 23, 2007.
C.P. Lanting, E. de Kleine, H.Bartels, D.R.M. Langers, P. van Dijk; ‘Cortical and subcortical fMRI of unilateral tinnitus’. 30th ARO Midwinter Meeting 2007, Denver, Colorado, USA.
C.P. Lanting, M.J. Versluis, P.J. Koopmans, J.M. Hoogduin, ‘Tuning post-labeling delay time and labeling plane position of continuous arterial spin labeling at 3T’. ESMRMB Annual Meeting 2004, Copenhagen, Denmark.
M.J.Versluis, C.P. Lanting, P.J. Koopmans, J.M.Hoogduin,’Flow sensitised gradient recalled multi-echo SENSE EPI’. ESMRMB Annual Meeting 2004, Copenhagen, Denmark.
P. Koopmans, C.P. Lanting, M. Versluis, H. Hoogduin, ‘Development of a reference phantom for fMRI studies’. ISMRM scientific meeting 2004, Kyoto, Japan.